The official blog of Lauri Romanzi, MD

Ask Dr R: Overactive bladder and Enablex

Hi Dr. Romanzi,
I have been on Enablix 7.5 for almost 3 weeks now.  It had taken all my bladder symptoms away.  Now today they are creeping up again.  Can a medication just stop working like that?  I am afraid to go up to the 15mg for bad side effects.
Thanks,
Lori
Hello Lori,
Bladder infection, dietary irritants and stress can all alter the efficacy of medication. Whenever overactive bladder therapy starts, frequent visits to alter and change and double check bladder response and dysfunction are not at all uncommon. In the event you need the higher dose, it is unlikely you will have bothersome side effects if you did not have them at the lower dose. Some people just need the higher dose, and won’t sustain efficacy at the lower. By now, you’re likely due to return to the doctor who prescribed the medication, and all these issues will be considered.
Best Regards,
Dr R
Hi Dr. Romanzi,
I have been on Enablix 7.5 for almost 3 weeks now.  It had taken all my bladder symptoms away.  Now today they are creeping up again.  Can a medication just stop working like that?  I am afraid to go up to the 15mg for bad side effects.
Thanks,
Lori
Hello Lori,
Bladder infection, dietary irritants and stress can all alter the efficacy of medication. Whenever overactive bladder therapy starts, frequent visits to alter and change and double check bladder response and dysfunction are not at all uncommon. In the event you need the higher dose, it is unlikely you will have bothersome side effects if you did not have them at the lower dose. Some people just need the higher dose, and won’t sustain efficacy at the lower. By now, you’re likely due to return to the doctor who prescribed the medication, and all these issues will be considered.
Best Regards,
Dr R
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1 comment

1 Sandra { 02.06.11 at 3:53 pm }

Will side effects taper off after a period of time? I have been on Enablex for a month and the side effects started after two weeks. They are all gastrointestional.

Time to talk to the prescribing physician about side effects and methods to manage the side effects.

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